LIPCAR-HF

A prognostic marker of heart failure with impaired ejection fraction

Coordinator:

Florence Pinet Inserm1167, Institut Pasteur de Lille, University of Lille, Lille, Florence, France

Contact: pinet@pasteur-lille.fr

Partners:
Thomas Thum, Institute of Molecular and Translational Therapeutic Strategies, Hannover, Germany.
Javier Diez, Fundación para la Investigación Médica Aplicada, Pamplona, Spain
Serge Masson, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
Piotr Ponikowski, Wroclaw Medical University, Wroclaw, Poland

Research focus:
The objective of this project is the development of the long noncoding RNA (lncRNA) LIPCAR as a new diagnostic and prognostic marker for heart failure patients. In this project, we will measure circulating levels of LIPCAR in blood samples of cohorts of patients with different ranges of heart failure such as MI, cardiomyocyte stress/injury, inflammation and myocardial fibrosis and healthy controls in order to develop a new cardiac biomarker.